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Ether was used widely for surgeries but became less popular because of its flammability and its tendency to cause vomiting. In England, it was quickly replaced by chloroform, but this agent caused many deaths and lost popularity.
Although the Roman numeral for the number 4 has always been taught to have been "IV," according to historians, the ancient Romans probably used "IIII" most of the time. This is partially backed up by the fact that early grandfather clocks displayed IIII for the number 4 instead of IV. Early clockmakers apparently thought that the IIII balanced out the VIII (used for the number 8) on the clock face and that it just looked better.
Drying your hands with a paper towel will reduce the bacterial count on your hands by 45–60%.
The FDA recognizes 118 routes of administration.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.