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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
There are 20 feet of blood vessels in each square inch of human skin.
Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
There can actually be a 25-hour time difference between certain locations in the world. The International Date Line passes between the islands of Samoa and American Samoa. It is not a straight line, but "zig-zags" around various island chains. Therefore, Samoa and nearby islands have one date, while American Samoa and nearby islands are one day behind. Daylight saving time is used in some islands, but not in others—further shifting the hours out of sync with natural time.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.


