Author Question: Contrast the location and function of autoreceptors with postsynaptic receptors. What will be an ... (Read 37 times)

rosent76 · **on:** Jun 22, 2018

Contrast the location and function of autoreceptors with postsynaptic receptors.

What will be an ideal response?

Question 2

Explain the importance of serotonin reuptake-blocking drugs for the treatment of mental disorders.

What will be an ideal response?

johnharpe · **Reply #1 on:** Jun 22, 2018

Answer to Question 1

Answer: Autoreceptors often act to feed back negatively onto either synthesis of
neurotransmitters or to inhibit the release of transmitter; these are metabotropic effects involving second messengers. Postsynaptic receptors bind transmitter and either directly control an ion channel (ionotropic) or use a second-messenger to control an ion channel (metabotropic).

Answer to Question 2

Answer: Serotonin reuptake inhibitors block the serotonin transporter, thus allowing serotonin to remain in the synapse. These drugs are used clinically to treat depression, some anxiety disorders, and obsessive-compulsive disorder.