Compare and contrast the locations and synaptic functions of the ...

[moongchi]

Compare and contrast the locations and synaptic functions of the two types of acetylcholine receptors. Give an example of a drug that would antagonize each receptor type.
 
  What will be an ideal response?

Question 2

Describe the biosynthesis of acetylcholine. List three different means that would act to alter the release of acetylcholine.
 
  What will be an ideal response?

[joneynes]

Answer to Question 1

Answer: Nicotinic receptors are ionotropic and are located on muscle fibers and in the brain. Muscarinic receptors are metabotropic and are located in the brain. ACh is an agonist for both receptors. Curare blocks nicotinic receptors, while atropine blocks muscarinic receptors.

Answer to Question 2

Answer: ACh is formed from choline and acetyl-coA in the presence of choline
acetyltransferase. ACh is released into synapses and has effects at two receptor types: nicotinic and muscarinic. Action potentials release ACh; botulinum toxin prevents ACh release; black widow spider venom stimulates ACh release.

[moongchi]

Thank you

[joneynes]

No problem