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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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Illness; diuretics; laxative abuse; hot weather; exercise; sweating; caffeine; alcoholic beverages; starvation diets; inadequate carbohydrate consumption; and diets high in protein, salt, or fiber can cause people to become dehydrated.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Cucumber slices relieve headaches by tightening blood vessels, reducing blood flow to the area, and relieving pressure.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.