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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Approximately 25% of all reported medication errors result from some kind of name confusion.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.