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In 1886, William Bates reported on the discovery of a substance produced by the adrenal gland that turned out to be epinephrine (adrenaline). In 1904, this drug was first artificially synthesized by Friedrich Stolz.
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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Cytomegalovirus affects nearly the same amount of newborns every year as Down syndrome.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.