Which type of tolerance is directly dependent on factors such as frequency and amount of drug administered to the organism and is independent of the drug administration context?
a. pharmacokinetic tolerance
b. pharmacodynamic tolerance
c. both of these
d. neither of these
Question 2
Most research indicates that the brain system that underlies the primary reward properties of drugs of abuse and natural reinforcers like food and sex is the
a. reticular activating system
b. basal ganglia
c. hippocampus
d. mesolimbic dopamine system
Sublingual drug administration.
Therapeutic index: (a) Drug X has a therapeutic index of 4. (b) Drug Z has a therapeutic index of 2.
Compressibility factors of gases and vapors.
First-pass metabolism (biotransformation). Absorption of an orally administered drug.
The Four Primary Drug-Receptor Families
Alternative sigma factors for heat shock genes