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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Hyperthyroidism leads to an increased rate of metabolism and affects about 1% of women but only 0.1% of men. For most people, this increased metabolic rate causes the thyroid gland to become enlarged (known as a goiter).
Human kidneys will clean about 1 million gallons of blood in an average lifetime.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.