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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Interferon was scarce and expensive until 1980, when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing for mass cultivation and purification from bacterial cultures.
The average office desk has 400 times more bacteria on it than a toilet.
This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.