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Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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The FDA recognizes 118 routes of administration.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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More than 4.4billion prescriptions were dispensed within the United States in 2016.