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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
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In most climates, 8 to 10 glasses of water per day is recommended for adults. The best indicator for adequate fluid intake is frequent, clear urination.
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Medication errors are three times higher among children and infants than with adults.
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For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.