Lysozyme is an enzyme that breaks down bacterial cell walls and is found in your tears, mucus, and saliva. A mutation occurs in the gene for lysozyme that results in a lysine (a positively charged amino acid) being substituted for an arginine (also a positively charged amino acid). Do you think that the mutant lysozyme will function similarly to the normal lysozyme?
◦ yes, because both lysine and arginine are positively charged so the tertiary structure and therefore function should be similar
◦ no, because all changes in protein primary sequence result in functional differences
◦ no, because changing lysine to arginine will cause the protein to denature
◦ yes, because protein function stays the same no matter what mutations occur
Major parts of a cell.
cell movement
Induced-fit model of enzyme activity.
A pathway for homologous recombination to repair DNA double-strand breaks
Cell
Mouse Cell Nuclei During Meiosis