After reading the paragraph below, answer the questions that follow.
In a study of patients seeking assisted reproductive technology, researchers examined the level of FSH in each patient as well as the average number of oocytes they were able to retrieve. Here is an approximation of the data.
| | Younger than 33 | Older than 33 but younger than 37 | Older than 38 but younger than 41 | Older than 41 |
| FSH levels | baseline = 100% | 112% | 117% | 122% |
| Oocytes retrieved | 8.8 | 7.5 | 4.7 | 3.2 |
Source: Adapted from Barad, D. H., Weghofer, A., and Gleicher, N. (2007). Age-specific levels for basal follicle-stimulating hormone assessment of ovarian function.
Obstetrics & Gynecology, 109(6): 1404-1410.
What explanation might there be for the relationship between number of oocytes and the levels of FSH?
◦ It takes more FSH to develop more oocytes.
◦ The number of FSH receptors on the oocyte increase with age.
◦ Ovarian response to FSH declines with age.
◦ Oocytes in older women are larger and therefore need more FSH to produce them.
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