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As many as 28% of hospitalized patients requiring mechanical ventilators to help them breathe (for more than 48 hours) will develop ventilator-associated pneumonia. Current therapy involves intravenous antibiotics, but new antibiotics that can be inhaled (and more directly treat the infection) are being developed.

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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.

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In 1864, the first barbiturate (barbituric acid) was synthesized.

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By definition, when a medication is administered intravenously, its bioavailability is 100%.

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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.

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