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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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Many of the drugs used by neuroscientists are derived from toxic plants and venomous animals (such as snakes, spiders, snails, and puffer fish).
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The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.
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The familiar sounds of your heart are made by the heart's valves as they open and close.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.