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For about 100 years, scientists thought that peptic ulcers were caused by stress, spicy food, and alcohol. Later, researchers added stomach acid to the list of causes and began treating ulcers with antacids. Now it is known that peptic ulcers are predominantly caused by Helicobacter pylori, a spiral-shaped bacterium that normally exist in the stomach.

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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.

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The people with the highest levels of LDL are Mexican American males and non-Hispanic black females.

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This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.

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In 1864, the first barbiturate (barbituric acid) was synthesized.

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