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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.

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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.

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In 1864, the first barbiturate (barbituric acid) was synthesized.

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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.

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Historic treatments for rheumatoid arthritis have included gold salts, acupuncture, a diet consisting of apples or rhubarb, nutmeg, nettles, bee venom, bracelets made of copper, prayer, rest, tooth extractions, fasting, honey, vitamins, insulin, snow collected on Christmas, magnets, and electric convulsion therapy.

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