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Interferon was scarce and expensive until 1980, when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing for mass cultivation and purification from bacterial cultures.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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The most destructive flu epidemic of all times in recorded history occurred in 1918, with approximately 20 million deaths worldwide.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The B-complex vitamins and vitamin C are not stored in the body and must be replaced each day.