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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
Thyroid conditions may make getting pregnant impossible.