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By definition, when a medication is administered intravenously, its bioavailability is 100%.
When Gabriel Fahrenheit invented the first mercury thermometer, he called "zero degrees" the lowest temperature he was able to attain with a mixture of ice and salt. For the upper point of his scale, he used 96°, which he measured as normal human body temperature (we know it to be 98.6° today because of more accurate thermometers).
The strongest synthetic topical retinoid drug available, tazarotene, is used to treat sun-damaged skin, acne, and psoriasis.
Many of the drugs used by neuroscientists are derived from toxic plants and venomous animals (such as snakes, spiders, snails, and puffer fish).
Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.
![Continued harvest of (a) cod and (b) mountain sheep by humans has caused evolutionary changes in mat](https://biology-forums.com/gallery/47/medium_33_31_08_11_2_20_49_16361410.jpeg)
![The Black Death spread over much of Europe in a three-year period in the middle of the fourteenth ce](https://biology-forums.com/gallery/47/medium_273688_23_02_15_7_45_11_208612424.jpeg)