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The use of salicylates dates back 2,500 years to Hippocrates’s recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.
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Illicit drug use costs the United States approximately $181 billion every year.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Blood is approximately twice as thick as water because of the cells and other components found in it.
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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.