Question 1
Which of the following statements regarding the cell-mediated immune response is TRUE?
◦ Cytotoxic T lymphocytes do not require antigen presentation to become activated.
◦ Cytotoxic T lymphocytes kill by producing hydrogen peroxide.
◦ Helper T lymphocytes have no role in the activation of cytotoxic T lymphocytes.
◦ Cytotoxic T lymphocytes interact with antibodies that have bound antigen to identify their target.
◦ A single cytotoxic T lymphocyte can kill many target cells.
Question 2
The protozoan that causes malaria is an intracellular parasite of red blood cells (RBCs). An adaptive immune response to this parasite is problematic because
◦ the parasite damages leukocytes along with RBCs.
◦ red blood cells do not produce MHC and, therefore, do not display the fact that they have been infected by presenting antigen.
◦ RBCs never enter lymphoid tissue.
◦ complement cannot effectively destroy RBCs.
◦ RBCs normally produce cytokines necessary for adaptive immune response, which this infection prevents.
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