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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Vital signs (blood pressure, temperature, pulse rate, respiration rate) should be taken before any drug administration. Patients should be informed not to use tobacco or caffeine at least 30 minutes before their appointment.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The first successful kidney transplant was performed in 1954 and occurred in Boston. A kidney from an identical twin was transplanted into his dying brother's body and was not rejected because it did not appear foreign to his body.