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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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In 1886, William Bates reported on the discovery of a substance produced by the adrenal gland that turned out to be epinephrine (adrenaline). In 1904, this drug was first artificially synthesized by Friedrich Stolz.
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Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.