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In 1864, the first barbiturate (barbituric acid) was synthesized.
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More than one-third of adult Americans are obese. Diseases that kill the largest number of people annually, such as heart disease, cancer, diabetes, stroke, and hypertension, can be attributed to diet.
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In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
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This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.