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In 1864, the first barbiturate (barbituric acid) was synthesized.
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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
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Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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No drugs are available to relieve parathyroid disease. Parathyroid disease is caused by a parathyroid tumor, and it needs to be removed by surgery.