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Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.
An identified risk factor for osteoporosis is the intake of excessive amounts of vitamin A. Dietary intake of approximately double the recommended daily amount of vitamin A, by women, has been shown to reduce bone mineral density and increase the chances for hip fractures compared with women who consumed the recommended daily amount (or less) of vitamin A.
Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.