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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Russia has the highest death rate from cardiovascular disease followed by the Ukraine, Romania, Hungary, and Poland.
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
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Eat fiber! A diet high in fiber can help lower cholesterol levels by as much as 10%.