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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Cytomegalovirus affects nearly the same amount of newborns every year as Down syndrome.
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Your heart beats over 36 million times a year.
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More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.