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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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In 1835 it was discovered that a disease of silkworms known as muscardine could be transferred from one silkworm to another, and was caused by a fungus.
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According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
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Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.