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Elderly adults are living longer, and causes of death are shifting. At the same time, autopsy rates are at or near their lowest in history.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Medication errors are three times higher among children and infants than with adults.
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The immune system needs 9.5 hours of sleep in total darkness to recharge completely.