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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Of the estimated 2 million heroin users in the United States, 600,000–800,000 are considered hardcore addicts. Heroin addiction is considered to be one of the hardest addictions to recover from.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.