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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.
Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.