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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
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Vampire bats have a natural anticoagulant in their saliva that permits continuous bleeding after they painlessly open a wound with their incisors. This capillary blood does not cause any significant blood loss to their victims.
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The human body produces and destroys 15 million blood cells every second.
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.
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In 1864, the first barbiturate (barbituric acid) was synthesized.