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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.