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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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Complications of influenza include: bacterial pneumonia, ear and sinus infections, dehydration, and worsening of chronic conditions such as asthma, congestive heart failure, or diabetes.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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The human body produces and destroys 15 million blood cells every second.
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On average, the stomach produces 2 L of hydrochloric acid per day.