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Ether was used widely for surgeries but became less popular because of its flammability and its tendency to cause vomiting. In England, it was quickly replaced by chloroform, but this agent caused many deaths and lost popularity.
Women are two-thirds more likely than men to develop irritable bowel syndrome. This may be attributable to hormonal changes related to their menstrual cycles.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.