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More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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The toxic levels for lithium carbonate are close to the therapeutic levels. Signs of toxicity include fine hand tremor, polyuria, mild thirst, nausea, general discomfort, diarrhea, vomiting, drowsiness, muscular weakness, lack of coordination, ataxia, giddiness, tinnitus, and blurred vision.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.