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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
As of mid-2016, 18.2 million people were receiving advanced retroviral therapy (ART) worldwide. This represents between 43–50% of the 34–39.8 million people living with HIV.
The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.
The average human gut is home to perhaps 500 to 1,000 different species of bacteria.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.