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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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There are more nerve cells in one human brain than there are stars in the Milky Way.
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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
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Illicit drug use costs the United States approximately $181 billion every year.