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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
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Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.
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Nitroglycerin is used to alleviate various heart-related conditions, and it is also the chief component of dynamite (but mixed in a solid clay base to stabilize it).
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.