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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
Blood in the urine can be a sign of a kidney stone, glomerulonephritis, or other kidney problems.
In 1864, the first barbiturate (barbituric acid) was synthesized.
Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.
Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.