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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
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Acetaminophen (Tylenol) in overdose can seriously damage the liver. It should never be taken by people who use alcohol heavily; it can result in severe liver damage and even a condition requiring a liver transplant.
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The FDA recognizes 118 routes of administration.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.