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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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Ether was used widely for surgeries but became less popular because of its flammability and its tendency to cause vomiting. In England, it was quickly replaced by chloroform, but this agent caused many deaths and lost popularity.
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Medication errors are three times higher among children and infants than with adults.
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Nearly 31 million adults in America have a total cholesterol level that is more than 240 mg per dL.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.