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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
More than 50% of American adults have oral herpes, which is commonly known as "cold sores" or "fever blisters." The herpes virus can be active on the skin surface without showing any signs or causing any symptoms.
Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
Automated pill dispensing systems have alarms to alert patients when the correct dosing time has arrived. Most systems work with many varieties of medications, so patients who are taking a variety of drugs can still be in control of their dose regimen.
![Deciduous and permanent teeth. (A) The deciduous teeth, with the age of eruption given in months; (B](https://biology-forums.com/gallery/47/medium_14755_30_09_12_4_39_18_91421720.jpeg)
![H. erectus migrated out of Africa beginning about 1.8 million years ago and is first known from Geor](https://biology-forums.com/gallery/47/medium_275510_22_02_15_5_56_58_207731480.jpeg)