The nurse is assessing a female client's risk of developing breast cancer. Which family history finding would the nurse interpret as most significant?
◦ The client's maternal grandmother developed breast cancer at age 80.
◦ Breast cancer has not been diagnosed in the family in two generations.
◦ The client's brother was diagnosed with breast cancer at age 35.
◦ The client had a hysterectomy due to uterine fibroids.