Question 1
Two proteins interact to form a multimeric complex. When one of the proteins is mutated, there is a substantial loss of functional activity in the multimeric protein. This type of mutation is classified as ________.
◦ null/ amorphic
◦ hypomorphic
◦ hypermorphic
◦ neomorphic
◦ dominant negative
Question 2
Two pure-breeding mutant plants produce white flowers. When they are crossed, all of the progeny have wild-type purple flowers. What does this genetic complementation tell you?
◦ The genes are part of two distinct biosynthetic pathways.
◦ The two lines exhibit different mutations in the same gene.
◦ More than one gene is involved in determining the phenotype.
◦ The allele is pleiotropic.
◦ The allele exhibits incomplete dominance.