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Author Question: Why do origins of replication in various bacteria have conserved DNA consensus sequences? (Read 33 times)

cookcarl

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Why do origins of replication in various bacteria have conserved DNA consensus sequences?
◦ Consensus sequences are found throughout bacterial genomes and so would be found at the origin as well.
◦ The consensus sequence allows the origin to wrap into a circle and recruit replication initiation proteins.
◦ It is more efficient to use the same sequence multiple times in different genomes than to change it.
◦ Fewer mutations in the DNA occur at the very beginning of replication at the origin, hence why they are conserved as consensus sequences.
◦ Origins need to be recognized by replication initiation proteins to open up their AT-rich regions.


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Marked as best answer by cookcarl on Jan 12, 2022

jgranad15

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cookcarl

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Reply 2 on: Jan 12, 2022
:D TYSM


raenoj

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Reply 3 on: Yesterday
Excellent

 

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