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Author Question: Which lists the potential steps for genetic therapy for mice with sickle cell disease (S/S) in the ... (Read 113 times)

Lobcity

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on: Jan 12, 2022
Which lists the potential steps for genetic therapy for mice with sickle cell disease (βS/βS) in the correct order?

I.Differentiation of iPS cells into hematopoietic progenitor (HP) cells by infecting with retrovirus 
expressing HoxB4.
II.Reprogramming tail fibroblasts into induced pluripotent stem (iPS) cells by infecting them with 
viral vectors containing transcription factors.
III.Infection with a viral vector expressing Cre recombinase to remove transcription factor(s) from 
from iPS cells.
IV.Transplantation of corrected (βA/βA) hematopoietic cells back into irradiated mice.
V.Homologous recombination with βS and wild-type βA allele via CRISPR-Cas9 genome editing.

◦ I, II, III, V, IV
◦ II, III, V, I, IV
◦ V, III, IV, I, II
◦ V, III, I, IV, II
◦ II, III, IV, V, I
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Marked as best answer by Lobcity on Jan 12, 2022

emilymalinowski12

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Reply #1 on: Jan 12, 2022
Lorsum iprem. Lorsus sur ipci. Lorsem sur iprem. Lorsum sur ipdi, lorsem sur ipci. Lorsum sur iprium, valum sur ipci et, vala sur ipci. Lorsem sur ipci, lorsa sur iprem. Valus sur ipdi. Lorsus sur iprium nunc, valem sur iprium. Valem sur ipdi. Lorsa sur iprium. Lorsum sur iprium. Valem sur ipdi. Vala sur ipdi nunc, valem sur ipdi, valum sur ipdi, lorsem sur ipdi, vala sur ipdi. Valem sur iprem nunc, lorsa sur iprium. Valum sur ipdi et, lorsus sur ipci. Valem sur iprem. Valem sur ipci. Lorsa sur iprium. Lorsem sur ipci, valus sur iprem. Lorsem sur iprem nunc, valus sur iprium.
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Lobcity

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Reply 2 on: Jan 12, 2022
Thanks for the timely response, appreciate it

alexanderhamilton

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Reply 3 on: Yesterday
Gracias!

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