Question 1
To study the maximum amount of genome diversity in humans, which of the following provides the most information?
◦ karyotyping
◦ SNP variation
◦ DNA fingerprinting
◦ sequencing of one or more specific genes
◦ ortholog comparisons
Question 2
Transcomplementation is a name sometimes given for a test to see whether a gene from one organism can "rescue" a loss-of-function mutant of a different organism with a homologous gene. To which of the following processes might this term apply?
◦ replacement of a nonfunctional globin gene with a globin pseudogene
◦ substitution of a drought-resistant gene from potato plants with a drought-resistant gene from a cactus species
◦ introduction of a human
WEE1 gene into a yeast culture with
wee1- mutant yeast
◦ replacement of a
cdc25- with a
cdc13+ gene to rescue a cell cycle dysfunction
◦ use of
Drosophila heat shock gene promoters to regulate heat shock genes in
the model fish, fugu
Model Organism Drosophila
Histone and pol II CTD modifications as a function of gene position
The Turing Test
The current status of gene therapy worldwide
DNA sequence variation in parts of the Drosophila Adh gene
PCR analysis showing expansion of the CAG repeat region of the HD gene